Latest advances in the reversal strategies for direct oral anticoagulants.
Jean EscalJulien LanoiseléeGéraldine PoenouPaul ZuffereySilvy LaportePatrick MismettiXavier DelavennePublished in: Fundamental & clinical pharmacology (2024)
With the validation of specific and nonspecific antidotes, DOACs could supplant traditional oral anticoagulants. This progress represents a significant advancement in anticoagulation therapy. However, ongoing research is crucial to address remaining safety concerns of the specific reversion agents of DOACs in clinical practice.