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Impact of white matter hyperintensities on surrounding white matter tracts.

William ReginoldKevin SamJulien PoublancJoe FisherAdrian CrawleyDavid J Mikulis
Published in: Neuroradiology (2018)
White matter hyperintensities are associated with two patterns of altered diffusion characteristics in the surrounding white matter tract network. Diffusion characteristics along white matter tracts improve further away from white matter hyperintensities suggestive of a local penumbra pattern. Also, altered diffusion extends further along tracts traversing white matter hyperintensities suggestive of a Wallerian-type degenerative pattern.
Keyphrases
  • white matter
  • multiple sclerosis