Autophagy Is Independent of the Chondroprotection Induced by Platelet-Rich Plasma Releasate.

Fan YangHaoran HuWenjing YinGuangyi LiTing YuanXuetao Xie Chang-Qing Zhang

Published in: BioMed research international (2018)

PRP releasate promoted the anabolic gene expression, relieved inflammatory stress in chondrocytes, and ameliorated cartilage degeneration, but autophagy was independent of these processes.

Keyphrases

platelet rich plasma
gene expression
oxidative stress
cell death
endoplasmic reticulum stress
signaling pathway
extracellular matrix
dna methylation