Jiaohong pills attenuate neuroinflammation and amyloid-β protein-induced cognitive deficits by modulating the mitogen-activated protein kinase/nuclear factor kappa-B pathway.
Hong ZhangWeiyan CaiLijinchuan DongQing YangQi LiQingsen RanLi LiuYajie WangYujie LiXiaogang WengXiaoxin ZhuYing ChenPublished in: Animal models and experimental medicine (2024)
It was found that JHP reduced neuroinflammatory response in AD mice by targeting the MAPK/NF-κB signaling pathway.
Keyphrases
- nuclear factor
- signaling pathway
- toll like receptor
- pi k akt
- induced apoptosis
- epithelial mesenchymal transition
- high glucose
- lps induced
- diabetic rats
- traumatic brain injury
- lipopolysaccharide induced
- high fat diet induced
- inflammatory response
- oxidative stress
- drug induced
- protein protein
- protein kinase
- endothelial cells
- cognitive impairment
- type diabetes
- adipose tissue
- small molecule
- cell proliferation
- wild type