Familial associations for rheumatoid autoimmune diseases.

Hauke ThomsenXinjun LiKristina SundquistJan SundquistAsta FörstiKari Hemminki

Published in: Rheumatology advances in practice (2020)

The derived familial risks in this nationwide family study on medically diagnosed RAID are compatible with emerging evidence on the polygenic background of these complex diseases. Novel genetic pathways offer new therapeutic targets that alleviate disease onset optimally in high-risk familial patients and others.

Keyphrases

early onset
end stage renal disease
newly diagnosed
chronic kidney disease
prognostic factors
genome wide
gene expression
patient reported outcomes
systemic lupus erythematosus
dna methylation
patient reported