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Survival with novel hormonal therapies in patients with nonmetastatic castration-resistant prostate cancer: indirect comparison of three randomized phase-III trials.

Melania RivanoLuca CancanelliLorenzo Di SpazioDaniele MengatoMarco ChiumenteAndrea Messori
Published in: World journal of urology (2022)
While the Shiny method has confirmed its validity in reconstructing individual patient data, our indirect comparisons based on mature OS demonstrated similar efficacy and substantial equivalence among these three second-generation androgen receptor inhibitors.
Keyphrases
  • phase iii
  • open label
  • double blind
  • clinical trial
  • placebo controlled
  • phase ii
  • case report
  • electronic health record
  • big data
  • free survival
  • study protocol
  • metabolic syndrome
  • insulin resistance