Opposing effects of 25-hydroxy- and 1α,25-dihydroxy-vitamin D3 on pro-cachectic cytokine-and cancer conditioned medium-induced atrophy in C2C12 myotubes.
Hana SustovaMarilisa De FeudisSimone ReanoMaraiza Alves TeixeiraIlaria ValleIvan ZaggiaEmanuela AgostiFlavia ProdamNicoletta FilighedduPublished in: Acta physiologica (Oxford, England) (2019)
Altogether these data might explain the lack of efficacy of VD treatment in vivo for the protection of muscle mass in cancer.