Association between particulate matter containing EPFRs and neutrophilic asthma through AhR and Th17.

Jeffrey N HardingMaureen GrossVivek PatelSteven PotterStephania A Cormier

Published in: Respiratory research (2021)

Collectively, our data corroborates that PM initiates an eTh17 specific inflammatory response causing neutrophilic asthma through pathways in epithelial, dendritic, and T cells that promote eTh17 differentiation during initial PM exposure.

Keyphrases

particulate matter
air pollution
lung function
inflammatory response
chronic obstructive pulmonary disease
allergic rhinitis
lipopolysaccharide induced
electronic health record
cystic fibrosis
toll like receptor
big data
deep learning
data analysis
artificial intelligence
polycyclic aromatic hydrocarbons