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Waveguide-based absorption measurement system for visible wavelength applications.

P NeutensR JansenG WoronoffM RutowskaN HosseiniF BujaA HumbertF ColleT StakenborgWillem Van Roy
Published in: Biomedical optics express (2021)
We present a miniaturized waveguide-based absorption measurement system operating at a wavelength of 635 nm, based on a silicon nitride integrated photonic platform, suitable for lab-on-chip applications. We experimentally demonstrate a high correlation between the bulk dye concentration and the measured absorption loss levels in the waveguides. We explain a photonic design process for choosing the ideal waveguide to minimize the coefficient of variation on the analyte concentration. The approach is designed for camera readout, allowing multiple readouts and easy integration for lab-on chip cartridge approach.
Keyphrases
  • high throughput
  • high speed
  • circulating tumor cells
  • photodynamic therapy
  • quantum dots
  • magnetic resonance
  • magnetic resonance imaging
  • convolutional neural network
  • diffusion weighted imaging
  • visible light