Curcuma supplementation in high-fat-fed C57BL/6 mice: no beneficial effect on lipid and glucose profile or prevention of weight gain.

Caroline Bertoncini SilvaPriscila Giacomo FassiniLeandra Náira Zambelli RamalhoEdemilson Cardoso da ConceiçãoAline José Coelho Moreira ZordanDaniela CarlosVivian Marques Miguel Suen

Published in: European journal of nutrition (2019)

Curcuma supplementation did not prevent weight gain or improved glucose and lipid profile in mice receiving high-fat diet. Furthermore, there was evidence of possible curcuma toxicity in the pancreas of C57BL/6 mice. The implications of these findings on humans still need to be investigated.

Keyphrases

weight gain
high fat diet
body mass index
birth weight
high fat diet induced
insulin resistance
adipose tissue
weight loss
oxidative stress
wild type
skeletal muscle