The role of intraoperative radiotherapy in advanced rectal cancer: a meta-analysis.

Matthew R FahyMichael E KellyMegan Power FoleyTimothy S NugentConor J ShieldsDes C Winter

Published in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2021)

The addition of IORT to current treatment strategies in the management of patients with LARC/LRRC is associated with a lower rate of locoregional recurrence without increased morbidity. However, this marks a highly selective group of patients, with heterogeneity regarding indications, prior neoadjuvant treatments and/or IORT dosing.

Keyphrases

rectal cancer
locally advanced
squamous cell carcinoma
single cell
radiation therapy
early stage
patients undergoing
free survival
radiation induced