Pulmonary Complications Secondary to Immune Checkpoint Inhibitors.
Hasan Ahmad Hasan AlbitarNarjust DumaKonstantinos LeventakosAlice Gallo de MoraesPublished in: International journal of chronic diseases (2020)
Melanoma was the most common malignancy, the majority of patients had grade 2 pneumonitis and required treatment with steroids, and all patients affected by ICI-related pneumonitis had stage IV malignancy. Potential risk factors included smoking history, prior radiotherapy, obesity, and advance stage at the time of ICI initiation. Extrapulmonary irAEs are common in patients with pneumonitis.
Keyphrases
- end stage renal disease
- risk factors
- newly diagnosed
- chronic kidney disease
- ejection fraction
- prognostic factors
- early stage
- metabolic syndrome
- rheumatoid arthritis
- pulmonary hypertension
- squamous cell carcinoma
- interstitial lung disease
- risk assessment
- adipose tissue
- patient reported outcomes
- idiopathic pulmonary fibrosis
- smoking cessation
- physical activity
- radiation induced