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Age-stratified profiles and outcomes of patients with heart failure with preserved ejection fraction.

Shinsuke YamanakaKotaro NochiokaHideka HayashiTakashi ShirotoJun TakahashiSatoshi MiyataSatoshi YasudaHiroaki Shimokawanull null
Published in: ESC heart failure (2024)
Younger HFpEF patients (≤64 years) exhibit a male predominance, elevated BMI, and poorly controlled diabetes, highlighting the importance of glycaemic control in reducing SCD risk. Older HFpEF patients (≥65 years) are more likely to be female, with multiple comorbidities linked to an increased risk of HF-related mortality. These findings underscore the need for physicians to recognize age-related, distinct HFpEF phenotypes for personalized patient management.
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