COVID-19 vaccination in Sindh Province, Pakistan: A modelling study of health impact and cost-effectiveness.
Carl A B PearsonFiammetta Maria BozzaniSimon R ProcterNicholas G DaviesMaryam HudaHenning Tarp JensenMarcus Keogh-BrownMuhammad KhalidSedona SweeneySergio Torres-Ruedanull nullnull nullRosalind M M EggoAnna VassallMark JitPublished in: PLoS medicine (2021)
COVID-19 vaccination can have a considerable health impact and is likely to be cost-effective if more optimistic vaccine scenarios apply. Preventing severe disease is an important contributor to this impact. However, the advantage of prioritising older, high-risk populations is smaller in generally younger populations. This reduction is especially true in populations with more past transmission, and if the vaccine is likely to further impede transmission rather than just disease. Those conditions are typical of many low- and middle-income countries.