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Can radiation-induced lower urinary tract disease be ameliorated in patients treated for pelvic organ cancer: ICI-RS 2019?

J L H Ruud BoschKaren D McCloskeyAmit BahlSalvador ArlandisJeremy OckrimJeffrey WeissTamsin J Greenwell
Published in: Neurourology and urodynamics (2020)
We conclude that RT-induced negative effects on the LUT represent a significant clinical problem. Although this has been reduced with improved methods of delivery to spare normal tissue, we need to (a) discover better approaches to protect normal tissue and (b) develop effective treatments to reverse radiation damage.
Keyphrases
  • radiation induced
  • urinary tract
  • radiation therapy
  • papillary thyroid
  • oxidative stress
  • high glucose
  • rectal cancer
  • squamous cell
  • squamous cell carcinoma
  • endothelial cells