Early Kidney Damage Markers after Deferasirox Treatment in Patients with Thalassemia Major: A Case-Control Study.
Hamidreza BadeliAdel BaghersalimiSajjad EslamiFarshid SaadatAfagh Hassanzadeh RadRokhsar BasavandSoghra Rafiei PapkiadehBahram DarbandiWesam KootiIlaria PelusoPublished in: Oxidative medicine and cellular longevity (2019)
The findings of this study indicate that after taking deferasirox, there was renal damage and an increase in inflammatory factors. Also, minor renal impairment was observed after deferoxamine administration, but it was not confirmed at the molecular level (U. NGAL and KIM-1). Therefore, it seems that patients who are taking these two drugs should be monitored carefully.