Design of 1,4-Dihydropyridine Hybrid Benzamide Derivatives: Synthesis and Evaluation of Analgesic Activity and Their Molecular Docking Studies.
Idhayadhulla AkbarSurendrakumar RadhakrishnanKarpakavalli MeenakshisundaramAseer ManilalAshraf Atef HatamlehBassam Khalid AlnafisiAnis AhamedRavindran BalasubramaniPublished in: Drug design, development and therapy (2022)
In this study, all the synthesized compounds were found to possess significant analgesic activities; particularly, the performance of compound 2c is excellent. Thus, the preparative method described is an apt route for developing novel therapeutic formulations.