Mutation of Beclin1 acetylation site at K414 alleviates high glucose-induced podocyte impairment in the early stage of diabetic nephropathy by inhibiting hyperactivated autophagy.
Jun XuYujie DengYingying KeYunxia ZhuPing WangQing YuChengqian LiBimin ShiPublished in: Molecular biology reports (2022)
These findings suggest that the acetylation site at K414 is a critical molecule and drug target and that further research into this area is warranted.