Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels.

Emanuele Felice OsimoLuke James BaxterGlyn LewisPeter B JonesGolam M Khandaker

Published in: Psychological medicine (2019)

About a quarter of patients with depression show evidence of low-grade inflammation, and over half of patients show mildly elevated CRP levels. There are significant differences in the prevalence of low-grade inflammation between patients and matched healthy controls. These findings suggest that inflammation could be relevant to a large number of patients with depression.

Keyphrases

low grade
high grade
oxidative stress
end stage renal disease
depressive symptoms
ejection fraction
newly diagnosed
risk factors
patient reported