Overall and cause-specific mortality in the Sentinel system: A power analysis.

Richard S Swain Lockwood G TaylorTiffany S WoodworthCandace C FullerAndrew B PetroneTalia J MenzinNicole R HaugSengwee Toh Andrew D Mosholder

Published in: Pharmacoepidemiology and drug safety (2018)

This was the first study to investigate mortality data in the Sentinel death tables. We found that all-cause mortality appeared well powered for use as a safety outcome and cause-specific mortality outcomes may be adequately powered in certain circumstances. Further investigation into the quality of the Sentinel death data is needed.

Keyphrases

cardiovascular events
electronic health record
risk factors
big data
cardiovascular disease
coronary artery disease
data analysis
deep learning
weight loss
insulin resistance