The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target.

Qays KharoufA Marie PhillipsLauren E BleakleyEmma MorrisroeJulia OyrerLinghan JiaAndreas LudwigLiang JinJoseph A NicolazzoElisabetta CerbaiM Novella RomanelliSteven PetrouChristopher A Reid

Published in: British journal of pharmacology (2020)

These data suggest the HCN4 channel as a potential pharmacologically relevant target for anti-seizure drugs that is likely to have a low side-effect liability in the CNS.

Keyphrases

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