Current pharmacotherapeutic strategies for Strongyloidiasis and the complications in its treatment.
Dora BuonfratePaola RodariBeatrice BardaWendy PageLloyd EinsiedelMatthew R WattsPublished in: Expert opinion on pharmacotherapy (2022)
The standard dose of ivermectin is 200 µg/kg single dose orally, but multiple doses might be needed in immunosuppressed patients. In the case of hyperinfection, repeated doses are recommended up to 2 weeks after clearance of larvae from biological fluids, with close monitoring and further dosing based on review. Subcutaneous ivermectin is used where there is impaired intestinal absorption/paralytic ileus. In pregnant or lactating women, studies have not identified increased risk with ivermectin use. However, with limited available data, a risk-benefit assessment should be considered for each case.