Synthesis of Amides and Nitriles from Vinyl Azides and p-Quinone Methides.
Chen LinYangyong ShenBo HuangYu LiuSunliang CuiPublished in: The Journal of organic chemistry (2017)
A divergent synthesis of amides and nitriles from vinyl azides and p-quinone methides (p-QMs) was developed. The p-QMs could be activated by BF3-Et2O and then nucleophilically attacked by vinyl azides, leading to divergent rearrangement toward amides and nitriles.
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