CC16 as an Inflammatory Biomarker in Induced Sputum Reflects Chronic Obstructive Pulmonary Disease (COPD) Severity.
Mengjie ChenKan XuYuting HeJianjun JinRuolin MaoLei GaoYi ZhangGang WangPeng GaoMin XieChunfang LiuZhihong ChenPublished in: International journal of chronic obstructive pulmonary disease (2023)
Low CC16 mRNA expression levels in induced sputum were associated with low FEV1%pred and a high SGRQ score in COPD patients. Sputum CC16 as a potential biomarker for predicting COPD severity in clinical practice might attribute to the involvement of CC16 in airway eosinophilic inflammation.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- cystic fibrosis
- mycobacterium tuberculosis
- pulmonary tuberculosis
- high glucose
- oxidative stress
- diabetic rats
- clinical practice
- end stage renal disease
- newly diagnosed
- ejection fraction
- prognostic factors
- chronic kidney disease
- drug induced
- peritoneal dialysis
- air pollution
- patient reported outcomes