Development and Validation of a Genomic Profile for the Omission of Local Adjuvant Radiation in Breast Cancer.

Martin SjostromAnthony FylesFei-Fei LiuDavid McCreadyWei ShiKatrina Rey-McIntyreS Laura ChangFelix Y Feng Corey W Speers Lori J Pierce Erik Carl Viktor Holmberg Mårten FernöPer MalmströmPer Karsson

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)

The novel POLAR genomic signature on the basis of LRR biology may identify patients with a low risk of LRR despite not receiving RT, and thus may be candidates for RT omission.

Keyphrases

copy number
early stage
ionic liquid
gene expression
genome wide