HIV-1 inhibits haematopoiesis via microRNA secreted by virus-infected CD4+ T cells.

Usha Padmanabhan Ritwik Dahake Abhay S Chowdhary Prasad S Koka

Published in: European journal of haematology (2019)

In this study, we have identified two miRNAs, miR-15a and miR-24 secreted from purified HIV-1-infected CD4+ T cells that inhibited CD34+ haematopoietic progenitor stem cell differentiation into myeloid and erythroid colonies in vitro.

Keyphrases

hiv infected
antiretroviral therapy
cell proliferation
long non coding rna
long noncoding rna
human immunodeficiency virus
hiv positive
hiv aids
bone marrow
acute myeloid leukemia
dendritic cells
hepatitis c virus
hiv testing
south africa