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Engineering a multi-target therapy nanoplatform against tumor growth and metastasis via a novel NSAID-Pt(IV) prodrug.

Di ZhangJing NieDongbo WangHuina WuLei SunXuejian WangJiyong Wu
Published in: Chemical communications (Cambridge, England) (2022)
Tumor growth and metastasis are caused by many factors. The complexity means that a multi-target combination therapy strategy should be selected against tumor growth and metastasis. Here, cisplatin (CDDP) and bendazac (Ben) were designed as a novel NSAID-Pt(IV) nanoplatform, which is an effective weapon for combating tumor growth and metastasis.
Keyphrases
  • combination therapy
  • photodynamic therapy
  • cancer therapy
  • stem cells
  • drug release
  • mesenchymal stem cells