PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study.
Koji TanakaShoji MatsumotoGulibahaer AinidingIchiro NakaharaHidehisa NishiTetsuya HashimotoTsuyoshi OhtaNobutake SadamasaRyota IshibashiMasanori GomiMakoto SakaHaruka MiyataSadayoshi WatanabeTakuya OkataKazutaka SonodaJunpei KogeKyoko M IinumaKonosuke FurutaIzumi NagataKeitaro MatsuoTakuya MatsushitaNoriko IsobeRyo YamasakiJun-Ichi KiraPublished in: PloS one (2021)
Carrying ≥1 PON1 192R allele is associated with HPR by original and corrected PRU with clopidogrel in patients undergoing elective neurointervention, although alternative results related to other genetic polymorphisms cannot be excluded.