Cognitive functioning in essential tremor without dementia: a clinical and imaging study.
Fabiana NovellinoValeria SaccàMaria SalsoneGiuseppe NicolettiAndrea QuattroneCarmelina ChiriacoJosé L M MadrigalAldo QuattronePublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)
This study improves the knowledge on cognitive impairment in ET, as our findings demonstrate a heterogeneous pattern of cognitive dysfunction involving memory, executive function, and language domains in the ET group. This clinical profile relates with the deep involvement of the cerebellum and its connections with large-scale brain structures, suggesting that changes spreading in wide-ranging brain pathways may contribute to the physiopathology of cognitive dysfunction in ET.