ANGPTL2 is associated with an increased risk of cardiovascular events and death in diabetic patients.

Barnabas GellenNathalie Thorin-TrescasesPhilippe SosnerElise GandPierre-Jean SaulnierStéphanie RagotMathilde FratyStéphanie LaugierGrégory DucrocqDavid MontaignePierre LlatyVincent RigalleauPhilippe ZaouiJean-Michel HalimiRonan RousselEric ThorinSamy Hadjadj

Published in: Diabetologia (2016)

In patients with type 2 diabetes, serum ANGPTL2 concentrations were independently associated with death and MACE. Therefore, ANGPTL2 is a promising candidate biomarker for improving risk stratification in type 2 diabetes patients, and may prove to be a valuable therapeutic target.

Keyphrases

cardiovascular events
type diabetes
end stage renal disease
coronary artery disease
cardiovascular disease
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
insulin resistance
metabolic syndrome
glycemic control
patient reported outcomes
skeletal muscle