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Mutations in the pmrB gene constitute the major mechanism underlying chromosomally encoded colistin resistance in clinical Escherichia coli.
Jung-Chung Lin
Leung-Kei Kristopher Siu
Feng-Yee Chang
Ching-Hsun Wang
Published in:
Journal of global antimicrobial resistance (2024)
Colistin resistance mediated by amino acid substitutions in PmrB is a major chromosomally encoded mechanism in E. coli of clinical origin.
Keyphrases
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escherichia coli
klebsiella pneumoniae
amino acid
pseudomonas aeruginosa
acinetobacter baumannii
multidrug resistant
drug resistant
gram negative
biofilm formation
genome wide
copy number
transcription factor
cystic fibrosis