Neurogenic Orthostatic Hypotension: State of the Art and Therapeutic Strategies.
Dinesh K KalraAnvi RainaSumit SohalPublished in: Clinical Medicine Insights. Cardiology (2020)
Neurogenic orthostatic hypotension (nOH) is a subtype of orthostatic hypotension in which patients have impaired regulation of standing blood pressure due to autonomic dysfunction. Several primary and secondary causes of this disease exist. Patients may present with an array of symptoms making diagnosis difficult. This review article addresses the epidemiology, pathophysiology, causes, clinical features, and management of nOH. We highlight various pharmacological and non-pharmacological approaches to treatment, and review the recent guidelines and our approach to nOH.
Keyphrases
- end stage renal disease
- blood pressure
- ejection fraction
- newly diagnosed
- chronic kidney disease
- spinal cord injury
- peritoneal dialysis
- prognostic factors
- type diabetes
- heart rate
- risk factors
- oxidative stress
- metabolic syndrome
- insulin resistance
- patient reported outcomes
- physical activity
- weight loss
- mass spectrometry
- hypertensive patients