Evaluation of Heart Rate Variability and Endothelial Function 3 Months After Bariatric Surgery.
Tassia Gomide BragaMaria das Graças Coelho de SouzaPriscila Alves MaranhãoMichel MenezesLudmilla Dellatorre-TeixeiraEliete BouskelaCarel W Le RouxLuiz Guilherme Kraemer-AguiarPublished in: Obesity surgery (2021)
We investigated endothelial and autonomic nervous functions after bariatric surgery. For this, we prospectively recruited 40 patients for bariatric surgery or medical treatment (20 in each group). Heart rate variability (HRV) and endothelial function were evaluated before and 3 months after treatments. Glucagon-like peptide 1 (GLP-1), insulin, and glucose at fasting and 30 and 60 min after a standard 300-kcal meal were also analyzed. Surgery but not medical care increased HRV in all time-domain variables, while frequency-domain variables, vascular elasticity, and endothelial reactivity did not change. Changes in GLP-1 and insulin resistance markers did not correlate with HRV. After 3 months, bariatric surgery improved the parasympathetic activity of cardiac autonomic function. Trial registration: NCT03911479.
Keyphrases
- heart rate variability
- bariatric surgery
- heart rate
- insulin resistance
- end stage renal disease
- type diabetes
- weight loss
- obese patients
- endothelial cells
- minimally invasive
- newly diagnosed
- adipose tissue
- healthcare
- chronic kidney disease
- left ventricular
- peritoneal dialysis
- blood pressure
- prognostic factors
- clinical trial
- skeletal muscle
- heart failure
- high fat diet
- glycemic control
- phase iii
- mass spectrometry
- polycystic ovary syndrome
- coronary artery disease
- acute coronary syndrome
- atrial fibrillation
- percutaneous coronary intervention
- replacement therapy