Oncolytic virotherapies for pediatric tumors.

Evan G GrossMohammad A HamoDagoberto Estevez-OrdonezNicholas Mb LaskayTravis J AtchleyJames M JohnstonJames M Markert

Published in: Expert opinion on biological therapy (2023)

Substantial progress has been made in the past 10 years regarding the clinical use of OVT. From our review, OVT has favorable safety profiles compared to chemotherapy and radiation treatment. However, the antitumor effects of OVT remain variable depending on tumor type and viral agent used. Although the widespread adoption of OVT faces many challenges, we are optimistic that OVT will play an important role alongside standard chemotherapy and radiotherapy for the treatment of malignant pediatric solid tumors in the future.

Keyphrases

locally advanced
early stage
sars cov
electronic health record
rectal cancer