Bariatric Surgery Is Associated with Lower Concentrations of Fecal Secondary Bile Acids and Their Metabolizing Microbial Enzymes: A Pilot Study.
Hisham HussanMohamed R AliVictoria LyoAmy WebbMaciej PietrzakJiangjiang ZhuFouad ChoueiryHong LiBethany P CummingsMaria L MarcoValentina MediciSteven K ClintonPublished in: Obesity surgery (2024)
Concentrations of LCA, a secondary BA, and bacterial genes needed for BA metabolism are lower post-BRS. These changes can impact health and modulate the colorectal cancer cascade. Further research is warranted to examine how surgical alterations and the associated dietary changes impact bile acid metabolism.