Effect of Chronic Alcohol Abuse on Anabolic and Catabolic Signaling Pathways in Human Skeletal Muscle.

Boris S ShenkmanSvetlana P BelovaOlga E ZinovyevaNudlya D SamkhaevaTimur M MirzoevNatalia A VilchinskayaErzhena G AltaevaOlga V TurtikovaTatiana Y KostrominovaTatiana L Nemirovskaya

Published in: Alcoholism, clinical and experimental research (2017)

At the early stages of alcohol misuse in humans, changes in the regulation of anabolic and catabolic signaling pathways precede the development of skeletal muscle atrophy and manifestation of clinical symptoms of alcoholic myopathy.

Keyphrases

skeletal muscle
signaling pathway
insulin resistance
endothelial cells
pi k akt
alcohol consumption
chronic pain
epithelial mesenchymal transition
induced pluripotent stem cells
late onset
liver injury
metabolic syndrome
cell proliferation
muscular dystrophy