Presence and Implications of Anti-Angiotensin Converting Enzyme-2 Immunoglobulin M Antibodies in Anti-Melanoma-Differentiation-Associated 5 Dermatomyositis.
Christopher A MecoliAkira YoshidaJulie J PaikCheng Ting LinSonye DanoffHironari HanaokaAntony RosenLisa Christopher-StineMasataka KuwanaLivia A Casciola-RosenPublished in: ACR open rheumatology (2022)
We describe anti-ACE2 IgM autoantibodies in two independent cohorts with anti-MDA5-positive DM. These autoantibodies may be biomarkers for severe disease and provide insight into disease pathogenesis.