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Physiological constraints dictate toxin spatial heterogeneity in snake venom glands.

Taline D KazandjianBrett R HamiltonSamuel D RobinsonSteven R HallKeirah E BartlettPaul RowleyMark C WilkinsonNicholas R CasewellEivind A B Undheim
Published in: BMC biology (2022)
Our findings suggest that heterogeneous distributions of toxins are not an adaptation to controlling venom composition in snakes. Instead, it likely reflects physiological constraints on toxin production by the venom glands, opening avenues for future research on the mechanisms of functional differentiation of populations of protein-secreting cells within adaptive contexts.
Keyphrases
  • escherichia coli
  • induced apoptosis
  • cell cycle arrest
  • current status
  • endoplasmic reticulum stress
  • signaling pathway
  • cell death
  • amino acid
  • cell proliferation
  • small molecule