Circulating Liver-enriched Antimicrobial Peptide-2 Decreases During Male Puberty.
Tero VarimoPäivi J MiettinenKirsi VaaralahtiJorma ToppariHanna HuopioRaimo VoutilainenSirpa TenholaMatti HeroTaneli RaivioPublished in: Journal of the Endocrine Society (2022)
Circulating LEAP2 levels decreased after induction of puberty reciprocally with increased growth rate and energy demand, reflecting the metabolic state of the adolescent. Further, the results suggest that estradiol levels may have a permissive role in downregulating circulating LEAP2 levels.