Urinary angiotensin-converting enzyme 2 and metabolomics in COVID-19-mediated kidney injury.

Ander VergaraKaiming WangDaniele ColomboMahmoud GheblawiJaslyn RasmusonRupasri MandalFranca Del NonnoBrian ChiuJames W ScholeyMaria José SolerDavid S WishartGavin Y Oudit

Published in: Clinical kidney journal (2022)

Elevated uACE2 is related to AKI in patients with COVID-19. The loss of tubular ACE2 during SARS-CoV-2 infection demonstrates a potential link between aminoaciduria and proximal tubular injury.

Keyphrases

angiotensin converting enzyme
angiotensin ii
coronavirus disease
sars cov
respiratory syndrome coronavirus
high glucose
acute kidney injury
mass spectrometry
human health
climate change