Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56 bright CD16 - subset.
Irene VenezianiClaudia AlicataAndrea PelosiNadine LandolinaBiancamaria RicciValentina D'OriaAnna FagottiGiovanni ScambiaLorenzo MorettaEnrico MaggiPublished in: Journal for immunotherapy of cancer (2022)
These data highlight the potential value of TLR8 in NK cells as a new target for immunotherapy in patients with cancer.