Citrus maxima (Brum.) Merr. (Rutaceae): Bioactive Chemical Constituents and Pharmacological Activities.
Biswash SapkotaHari Prasad DevkotaPrakash PoudelPublished in: Evidence-based complementary and alternative medicine : eCAM (2022)
Citrus maxima (Burm). Merr. (family Rutaceae), commonly known as Pomelo, is an ethnomedicinally, pharmacologically, and phytochemically valued species. Various ethnomedicinal reports have revealed the use of C. maxima for cough, fever, asthma, diarrhea, ulcer, and diabetes and as a sedative. Numerous phytochemicals have been reported from C. maxima such as polyphenols, terpenoids, sterols, carotenoids, vitamins, and amino acids. The plant possesses significant bioactivities like antioxidant, antimicrobial, anti-inflammatory, analgesic, anticancer, antidiabetic, anti-Alzheimer's disease, insecticidal, anxiolytic, hepatoprotective, antimalarial, and antiobesity. Extensive research is necessary to explore the detailed mechanism of action of extracts and compounds to design effective medicines, herbal products, and functional foods.
Keyphrases
- anti inflammatory
- type diabetes
- amino acid
- cardiovascular disease
- chronic obstructive pulmonary disease
- staphylococcus aureus
- oxidative stress
- lung function
- single cell
- cognitive decline
- emergency department
- glycemic control
- neuropathic pain
- metabolic syndrome
- spinal cord injury
- spinal cord
- adverse drug
- skeletal muscle
- electronic health record
- insulin resistance
- plasmodium falciparum