A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells.

Hee-Yeon KimYounghay LeeHee-Soo YoonYu-Hee KimKyong-A ChoSo-Youn WooHan Sun KimBo-Young ParkSung-Chul JungInho JoWoo-Jae ParkJoo-Won ParkKyung-Ha Ryu

Published in: Tissue engineering and regenerative medicine (2020)

These results imply that TMSCs can differentiate into functional estrogen-secreting cells, thus providing a novel, alternative cell therapy for estrogen deficiency.

Keyphrases

induced apoptosis
cell cycle arrest
estrogen receptor
single cell
endoplasmic reticulum stress
oxidative stress
cell death