LL-37 promotes neutrophil extracellular trap formation in chronic rhinosinusitis with nasal polyps.
Yujie CaoFenghong ChenYueqi SunHaiyu HongYihui WenYinyan LaiZhaofeng XuXin LuoYang ChenJianbo ShiHua-Bin LiPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019)
Neutrophil extracellular traps are significantly increased in nasal polyps and LL-37 induces NET formation in CRSwNP patients. These findings indicate that NETs may contribute to the pathogenesis of neutrophilic inflammation in CRSwNP.