[Preparation of Salviae Miltiorrhiza and Ligustrazine Hydrochloride Nasal Thermosensitive in Situ Gel and Study on Characterization of Its Nasal Mucosal Permeability].
Wang-qing HaoYu LinXu YuanQian GaoPublished in: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (2018)
The central composite design-response surface methodolog was stable and feasible for preparation of nasal thermosensitive in situ gel of salviae miltiorrhiza and ligustrazine hydrochloride, the drug-loaded gel has sustained release effect.