Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome.
Jibril B HirboFrancesca PasuttoEric R GamazonPatrick EvansPriyanka PawarDaniel BernerJulia SealockRan TaoPeter S StraubAnuar I KonkashbaevMax A BreyerUrsula Schlötzer-SchrehardtAndré ReisMilam A BrantleyChiea C KhorKaren M JoosNancy J CoxPublished in: BMC genomics (2023)
Our results implicate a role for connective tissues and inflammation pathways in the etiology of XFS. Targeting the inflammatory pathway may be a potential therapeutic option to reduce progression in XFS.