Nanoparticle-based drug delivery for the treatment of traumatic brain injury.
Farrah S MohammedSacit Bulent OmayKevin N ShethJiangbing ZhouPublished in: Expert opinion on drug delivery (2022)
Nanoparticles are well suited to improve secondary outcomes as their multifunctionality and customizability enhance their potential for efficient targeted delivery, payload protection, increased brain penetration, low off-target toxicity, and biocompatibility in both acute and chronic timescales.
Keyphrases
- traumatic brain injury
- drug delivery
- liver failure
- drug induced
- white matter
- oxidative stress
- respiratory failure
- cancer therapy
- resting state
- type diabetes
- skeletal muscle
- functional connectivity
- human health
- metabolic syndrome
- climate change
- risk assessment
- blood brain barrier
- glycemic control
- tissue engineering
- subarachnoid hemorrhage