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Genetic polymorphisms of metabolic enzyme genes associated with leukocyte mitochondrial DNA copy number in PAHs exposure workers.

Xinling LiXiaoran DuanHui ZhangMingcui DingYanbin WangYongli YangWu YaoXiaoshan ZhouWei Wang
Published in: Cancer reports (Hoboken, N.J.) (2021)
The individuals carrying the AA genotype of GSTP1 rs1695 may have a lower mtDNAcn due to their weaker detoxification of PAHs.
Keyphrases
  • mitochondrial dna
  • copy number
  • polycyclic aromatic hydrocarbons
  • heavy metals
  • health risk assessment
  • human health
  • genome wide
  • dna methylation
  • risk assessment
  • peripheral blood
  • gene expression
  • climate change