Sustainable Difluoroalkylation Cyclization Cascades of 1,8-Enynes.

We reported a visible-light-induced difluoroalkylation and cyclization cascade reaction of 1,8-enynes with broad substrate scopes in up to 92% isolated yields. This method provides a sustainable and efficient access to the synthesis of difluoroalkylated tetracyclic compounds under mild conditions.