Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank.
Shan LuoShiu Lun Au YeungJie V ZhaoStephen BurgessCatherine Mary SchoolingPublished in: BMJ (Clinical research ed.) (2019)
Endogenous testosterone was positively associated with thromboembolism, heart failure, and myocardial infarction in men. Rates of these conditions are higher in men than women. Endogenous testosterone can be controlled with existing treatments and could be a modifiable risk factor for thromboembolism and heart failure.